Ahmed Adel Mansour KAMA, Ioannis MAVROUDIS, Alin-Stelian CIOBÎCĂ, Manuela PĂDURARIU
ABSTRACT :
Animal models are central to preclinical and occupational health research, particularly in studies investigating oxidative stress biomarkers such as MDA, SOD, CAT, and GPx. However, ethical misconduct in animal molecular biology, ranging from poor welfare practices to data fabrication, poses serious threats to scientific integrity, animal welfare, and public trust. This review summarizes key ethical frameworks, common forms of misconduct, and a documented case, drawing lessons relevant to occupational health research. Strong ethical oversight, transparent reporting, and continuous ethics training are essential to prevent misconduct and maintain credibility in molecular studies involving animal models.