Maria - Crinela ARDELEANU, Liana Gabriela SPRIDON, Alin Stelian CIOBÎCĂ
ABSTRACT :
Alzheimer’s disease (AD) is the most commonly encountered neurodegenerative disorder, characterized by a complex pathological profile marked by the accumulation of neurofibrillary tangles and amyloid plaques in the brain. Obtaining drug or natural treatments designed to improve patients’ lives is a topical issue, marked by numerous studies conducted both preclinically using animal models and clinically. Currently, many research studies focus on inducing an experimental model of Alzheimer’s disease with scopolamine and on using zebrafish as laboratory models for neurodegenerative pathologies, due in particular to their similarity to the human genome.