Cătălina IONESCU
ABSTRACT :
The Human Leukocyte Antigen (HLA) system represents a highly complex and polymorphic region of the human genome that plays a pivotal role in immune system function. The aim of this paper is to explore the genetic architecture and immunological significance of the Human Leukocyte Antigen (HLA) system, highlighting its role in disease susceptibility, transplant compatibility, and advancement of personalized medical approaches. By examining the polymorphic nature of HLA genes and their clinical implications, this study seeks to provide a comprehensive overview of how HLA contributes to both protective and pathological immune responses.