Ancuţa Andreea MILER, Mălina VISTERNICU Viorica RARINCA, Cătălina IONESCU, Vasile BURLUI, Alin-Stelian CIOBICĂ, Radu DĂNILĂ
ABSTRACT :
Thyroid diseases and obesity are two health conditions that frequently intersect and that can significantly influence the biochemical profile of patients. Obesity has a high prevalence among the global population, which is of concern because severe obesity is an important cause of mortality. However, surprisingly, obesity can be linked to several endocrine abnormalities, including thyroid dysfunction. Our study aims to evaluate changes in biochemical parameters, by standardized laboratory methods (e.g. spectrophotometric and potentiometric), in patients with thyroid dysfunction and obesity. By analyzing the clinical and laboratory data collected, we identified correlations between the levels of these parameters and the type of thyroid dysfunction. The results suggest that thyroid disorders can exacerbate changes in lipid profile and liver function, and obesity can contribute to the worsening of these effects. The aim of this study is to highlight the importance of comprehensive assessment of biochemical and hematological parameters in the management of patients with thyroid disease and obesity, providing insights for better targeted and personalized therapeutic strategies. The findings suggest that obese patients may exhibit significant alterations in biochemical and hematological parameters, and these alterations may reflect a complex interaction between thyroid function and overall metabolic status.