Valentina BURLACU, Viorica RARINCA
ABSTRACT :
This article aims to discuss the impact of exposure to low doses of pesticide mixtures on neurobehavioral effects, even at levels considered safe for individual compounds. These effects may be aggravated by specific conditions such as vitamin deficiency. Epidemiological and laboratory evidence supports a link between pesticide exposure and cognitive dysfunctions such as dementia, Parkinson’s disease, cancer, respiratory diseases, and reproductive disorders. Exposure to pesticides is associated with endocrine, dermatological, gastrointestinal, carcinogenic and reproductive disorders, with a significant number of cases of occupational poisoning,
especially among farmers. The neurological effects of pesticide exposure include memory loss, slower reaction times, impaired motor skills, and reduced visual ability. Pesticide poisoning represents a global public health problem, causing approximately 300,000 deaths worldwide annually. Dementia, characterized by mental decline, memory impairment, changes in social interpretation, and cognitive impairment, is a common consequence of pesticide exposure, often occurring after the age of 65. The main types of dementia, such as Alzheimer’s disease, are progressive and irreversible.